Development of neural circuits


Development of neural circuits

Diez Del Corral Lab

The nervous system is composed of a large variety of neuronal and glial cell types appropriately connected to reliably perform its functions, such as those sustaining basic survival (e.g. breathing) and behavioural responses to internal and external stimuli. We are currently focusing our work in the understanding of neural circuit formation during development and for this we are using the zebrafish larva as an animal model. We are particularly interested on the intersection of circuit formation and neuronal activity such as the role played by neuronal activity in circuit establishment and selection.

We work in collaboration with the Orger and de Polavieja groups.



If you are interested in joining our group, please contact Ruth Diez del Corral at the email address bellow.


Development of neural circuits

Know our Projects

The zebrafish is an ideal model system to analyse the formation of neuronal circuits during embryonic and postnatal development. A lot of work has been devoted to the discovery and understanding of the processes and mechanisms involved in dendritogenesis and axonogenesis at the cellular level but even the simplest circuits seem to involve distant brain/spinal cord regions. With the development of imaging and gene manipulation techniques it may be now possible to look at circuit formation in a more global way and in particular to address the role of early neuronal activity to shape formation of circuits.


Development of neural circuits

Know our Team

Ruth Diez del Corral

Ruth Diez del Corral, PhD

Research Associate

Mariana Viegas

Mariana Viegas

Masters Student


Know our Publications